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In just a few years everything has changed: our environment, our attitude to ageing and what we expect of our skin care products. And these changes have prompted the Clarins Research team, headed by Dr Lionel de Benetti, to define new priorities and ingredients for its global anti-ager. The first dual-phase intensive serum launched in 1985 as Double Serum, which since then has undergone four significant updates and today re-emerges much more effective as Generation 6.
What stays. More than ever before, the first objective of this serum is to stimulate the five biological functions which keep skin healthy and youthful: hydration, nutrition, oxygenation, protection and renewal. A global approach which re-activates every type of skin cell.
What’s changed. The addition of a second objective – to increase the skin’s
energy levels – and the line-up of key ingredients. Both instigated by new research, the critical changes in our environment, the widespread use of aggressive skin re-texturing treatments and increasing results-driven expectation.
Why a dual formula. The ultra-intensive concentration of water soluble and oil soluble ingredients only remain stable if stored in two separate bottles, mixed at the moment of application using the single pump. And because neither phase contains an emulsifier – used to combine oil and water soluble ingredients in one formula – the active ingredients are more mobile and better absorbed by the skin.
The age issues and how Generation 6 provides a global solution.
Hydration With age, the quality of the skins’ own protective hydrolipidic film deteriorates, resulting in moisture loss, greater sensitivity, lines and wrinkles. A process accelerated by the increasing use of micro-dermabrasion and chemical peels.
Generation 6 Restores the skin’s protective barrier and increases moisture levels by boosting the production of desmosomes, proteins which link together skin cells to limit moisture evaporation; increasing the production of NMF, the skin’s own moisture retaining factor; restoring skin barrier lipids; increasing the moisture retaining properties of all skin cells. Key ingredients… Salicornia extract, Kiwi and Macadamia oils and Codiavelane algae.
Nutrition The skin is the last organ to receive essential nutrients from our diet and with age, its needs are less likely to be so well met, leading to loss of firmness and comfort.
Generation 6 Provides the skin with a balanced and nourishing dose of Omega 3, 6 and 9 essential fatty acids, critical to the healthy development of cell membranes and the maintenance of skin elasticity. Key ingredients…Inca Peanut and Marula seed oil.
Oxygenation Stress and urban pollution inhibit the circulation. The knock on effect is a reduced supply of oxygen to the skin cells, which means that they lack the energy to be youthfully active and the skin loses radiance.
Generation 6 Increases the skin cells uptake of oxygen, leading to an increase in the skin’s energy levels, and relaxes the stress-constricted vessel walls of the skin’s microcirculation which in turn increases blood flow and results in a fresher, more radiant looking complexion. Key ingredients…London Rocket seed extract and super anti-oxidant Pycnogenol®, extracted from the bark of the Maritime Pine.
Protection Age, stress and environmental aggressors not only weaken the skin’s own defence system provided by the Langerhans cells, but they also encourage it to produce self-destructive free radicals and enzymes which accelerate the ageing process and damage skin-firming collagen and elastin.
Generation 6 Provides a triple level of protection by shielding the all important
Langerhans cells and blocking free radical and enzyme damage. It also restores skin comfort by soothing and reducing irritation. Key ingredients…Stimulen, a super-protective complex combining a tetrapeptide of four linked amino acids with Vitamin E, anti-oxidant Pycnogenol® and Camomile extract.
Renewal With age, the skin’s renewal rate slows down and the fibroblast cells produce less collagen and elastin, which means that the skin no longer looks as fresh and feels as firm.
Generation 6 Helps to increase cell renewal and in particular the number of fibroblasts and their production of collagen and elastin. This in turn restores freshness and firmness to the skin. Key ingredients…London Rocket seed extract, Centella Asiatica extract and Avocado oil.
Double Energy Boost
Some skins are too tired or stressed to fully benefit from a product’s active formula and a ‘kick-start’ of energy can make all the difference.
Generation 6
Supplies the skin with a mega-dose of vitamins which unleashes a burst of invaluable energy right at the heart of each cell. This not only kick-starts the skin’s response and increases the results you can hope to see, but it also helps to prevent age-related pigmentation by normalising melanin production. Key ingredients…a mega-dose of water and oil soluble Vitamin C, and a water and oil soluble Kiwi extract rich in Vitamin C, Provitamin A, Vitamins B and E. A highly effective mix and concentration of ingredients, only made possible because of the dual phase formula.
Texture and fragrance.
A light yet deeply comforting fluid serum which is absorbed immediately, with a fresh, floral fragrance of Mandarin, Jasmine and Rose on a warm base of Sandalwood and Amber.
Application.
Dispense three to four pumps in the palm of one hand, warm between both palms and massage lightly over the face, neck and décolleté, avoiding the eye area. Use in the evening on its own or under a night cream. For those who prefer to use it in the day, always top with a protective day cream. Suitable for all skin types, one bottle equates to an intensive course of treatment and depending on your skin’s needs it can be used as a global anti-ageing boost just a few times a year or on a daily basis.
Generation 6 Test Results
1.Restoring the skins protective barrier
To test the effectiveness of Generation 6 in restoring the skins hydrolipidic film, an in vitro study was carried out on a skin culture stripped of lipids by an organic solvent. After this process a green fluorescent marker was used to highlight filaggrin, a key component of the protective horny layer and a precursor of NMF, and it was found to be considerably weakened. The skin culture was then treated with Generation 6 and evaluated three hours later, clearly illustrating that the skin barrier had been restored.
2. Line-smoothing and firming
To test the effectiveness of Generation 6 at line-smoothing and firming skin, 35 women aged 40 to 55 used the product each evening for 4 weeks. The results recorded are the % improvement across all volunteers.

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New Generation 6 - Re-educating your skin to act young

In just a few years everything has changed: our environment, our attitude to ageing and what we expect of our skin care products. And these changes have prompted the Clarins Research team, headed by Dr Lionel de Benetti, to define new priorities and ingredients for its global anti-ager. The first dual-phase intensive serum launched in 1985 as Double Serum, which since then has undergone four significant updates and today re-emerges much more effective as Generation 6.
What stays. More than ever before, the first objective of this serum is to stimulate the five biological functions which keep skin healthy and youthful: hydration, nutrition, oxygenation, protection and renewal. A global approach which re-activates every type of skin cell.
What’s changed. The addition of a second objective – to increase the skin’s
energy levels – and the line-up of key ingredients. Both instigated by new research, the critical changes in our environment, the widespread use of aggressive skin re-texturing treatments and increasing results-driven expectation.
Why a dual formula. The ultra-intensive concentration of water soluble and oil soluble ingredients only remain stable if stored in two separate bottles, mixed at the moment of application using the single pump. And because neither phase contains an emulsifier – used to combine oil and water soluble ingredients in one formula – the active ingredients are more mobile and better absorbed by the skin.
Hydration With age, the quality of the skins’ own protective hydrolipidic film deteriorates, resulting in moisture loss, greater sensitivity, lines and wrinkles. A process accelerated by the increasing use of micro-dermabrasion and chemical peels.
Generation 6 Restores the skin’s protective barrier and increases moisture levels by boosting the production of desmosomes, proteins which link together skin cells to limit moisture evaporation; increasing the production of NMF, the skin’s own moisture retaining factor; restoring skin barrier lipids; increasing the moisture retaining properties of all skin cells. Key ingredients… Salicornia extract, Kiwi and Macadamia oils and Codiavelane algae.
Nutrition The skin is the last organ to receive essential nutrients from our diet and with age, its needs are less likely to be so well met, leading to loss of firmness and comfort.
Generation 6 Provides the skin with a balanced and nourishing dose of Omega 3, 6 and 9 essential fatty acids, critical to the healthy development of cell membranes and the maintenance of skin elasticity. Key ingredients…Inca Peanut and Marula seed oil.
Oxygenation Stress and urban pollution inhibit the circulation. The knock on effect is a reduced supply of oxygen to the skin cells, which means that they lack the energy to be youthfully active and the skin loses radiance.
Generation 6 Increases the skin cells uptake of oxygen, leading to an increase in the skin’s energy levels, and relaxes the stress-constricted vessel walls of the skin’s microcirculation which in turn increases blood flow and results in a fresher, more radiant looking complexion. Key ingredients…London Rocket seed extract and super anti-oxidant Pycnogenol®, extracted from the bark of the Maritime Pine.
Protection Age, stress and environmental aggressors not only weaken the skin’s own defence system provided by the Langerhans cells, but they also encourage it to produce self-destructive free radicals and enzymes which accelerate the ageing process and damage skin-firming collagen and elastin.
Generation 6 Provides a triple level of protection by shielding the all important
Langerhans cells and blocking free radical and enzyme damage. It also restores skin comfort by soothing and reducing irritation. Key ingredients…Stimulen, a super-protective complex combining a tetrapeptide of four linked amino acids with Vitamin E, anti-oxidant Pycnogenol® and Camomile extract.
Renewal With age, the skin’s renewal rate slows down and the fibroblast cells produce less collagen and elastin, which means that the skin no longer looks as fresh and feels as firm.
Generation 6 Helps to increase cell renewal and in particular the number of fibroblasts and their production of collagen and elastin. This in turn restores freshness and firmness to the skin. Key ingredients…London Rocket seed extract, Centella Asiatica extract and Avocado oil.
Some skins are too tired or stressed to fully benefit from a product’s active formula and a ‘kick-start’ of energy can make all the difference.
Supplies the skin with a mega-dose of vitamins which unleashes a burst of invaluable energy right at the heart of each cell. This not only kick-starts the skin’s response and increases the results you can hope to see, but it also helps to prevent age-related pigmentation by normalising melanin production. Key ingredients…a mega-dose of water and oil soluble Vitamin C, and a water and oil soluble Kiwi extract rich in Vitamin C, Provitamin A, Vitamins B and E. A highly effective mix and concentration of ingredients, only made possible because of the dual phase formula.
A light yet deeply comforting fluid serum which is absorbed immediately, with a fresh, floral fragrance of Mandarin, Jasmine and Rose on a warm base of Sandalwood and Amber.
Dispense three to four pumps in the palm of one hand, warm between both palms and massage lightly over the face, neck and décolleté, avoiding the eye area. Use in the evening on its own or under a night cream. For those who prefer to use it in the day, always top with a protective day cream. Suitable for all skin types, one bottle equates to an intensive course of treatment and depending on your skin’s needs it can be used as a global anti-ageing boost just a few times a year or on a daily basis.
1.Restoring the skins protective barrier
To test the effectiveness of Generation 6 in restoring the skins hydrolipidic film, an in vitro study was carried out on a skin culture stripped of lipids by an organic solvent. After this process a green fluorescent marker was used to highlight filaggrin, a key component of the protective horny layer and a precursor of NMF, and it was found to be considerably weakened. The skin culture was then treated with Generation 6 and evaluated three hours later, clearly illustrating that the skin barrier had been restored.
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Lipid stripped skin. Weak green fluorescence indicates a greatly weakened skin barrier | Generation 6 Treated Skin. Three hours later strong green fluorescence indicates a restored barrier, |
To test the effectiveness of Generation 6 at line-smoothing and firming skin, 35 women aged 40 to 55 used the product each evening for 4 weeks. The results recorded are the % improvement across all volunteers.













